The Ottoman wintering in Toulon occurred during the winter of 1543–44, following the Franco-Ottoman Siege of Nice, as part of the combined operations under the Franco-Ottoman alliance.
The Ottomans were offered by Francis I of France to winter at Toulon so that they could continue to harass the Holy Roman Empire, and especially the coast of Spain and Italy, as well the communications between the two countries:
"Lodge the Lord Barbarossa sent to the king by the Great Turk, with his Turkish Army and grands seigneurs to the number of 30,000 combattants during the winter in his town and port of Toulon... for the accommodation of the said army as well as the well-being of all this coast, it will not be suitable for the inhabitants of Toulon to remain and mingle with the Turkish nation, because of difficulties which might arise."
Only the heads of households were allowed to remain in the city, with the rest of the population having to leave, on pain of death. Francis I indemnified the inhabitants by exempting them from the taille tax for a period of 10 years.
During the wintering of Barbarossa, the Toulon Cathedral was transformed into a mosque, the call to prayer occurred five times a day, and Ottoman coinage was the currency of choice. According to an observer: "To see Toulon, one might imagine oneself at Constantinople".
Throughout the winter, the Ottomans were able to use Toulon as a base to attack the Spanish and Italian coasts under Admiral Salih Reis. They raided and bombarded Barcelona in Spain, and Sanremo, Borghetto Santo Spirito, Ceriale in Italy, and defeated Italo-Spanish naval attacks. Christian slaves were being sold in Toulon throughout the period.