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Omsk hemorrhagic fever

Omsk hemorrhagic fever
Classification and external resources
Specialty infectious disease
ICD-10 A98.1
ICD-9-CM 065.1
DiseasesDB 31095
MeSH D006481
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Omsk hemorrhagic fever virus
Virus classification
Group: Group IV ((+)ssRNA)
Family: Flaviviridae
Genus: Flavivirus
Species: Omsk hemorrhagic fever virus

Omsk hemorrhagic fever is a viral hemorrhagic fever caused by a Flavivirus.

It is found in Siberia. It is named for an outbreak in Omsk.

There are a number of symptoms of the virus. In the first 1–8 days the first phase begins. The symptoms in this phase are:

In 1–2 weeks, some people may recover, although others might not. They might experience a focal hemorrhage in mucosa of gingival, uterus, and lungs, a papulovesicular rash on the soft palate, cervical lymphadenopathy (it occurs in the neck which that enlarges the lymph glandular tissue), and occasional neurological involvement. If the patient still has OHF after 3 weeks, then a second wave of symptoms will occur. It also includes signs of encephalitis. In most cases if the sickness does not fade away after this period, the patient will die. Patients that recover from OHF may experience hearing loss, hair loss, and behavioral or psychological difficulties associated with neurological conditions.

Omsk hemorrhagic fever is caused by the Omsk hemorrhagic fever virus (OHFV), a member of the Flavivirus family. The virus was discovered by Mikhail Chumakov and his colleagues between 1945 and 1947 in Omsk, Russia. The infection is found in western Siberia, in places including Omsk, Novosibirsk, Kurgan, and Tyumen. The virus survives in water and is transferred to humans via contaminated water or an infected tick.

The main hosts of OHFV are rodents like the non-native muskrat. OHFV originates in ticks, who then transmit it to rodents by biting them. Humans become infected through tick bites or contact with a muskrat. Humans can also become infected through contact with blood, feces or urine of a dead or sick muskrat (or any type of rat). The virus can also spread through milk from infected goats or sheep. There is no evidence that the virus is contagious among humans.


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