ORC6L

ORC6
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 3M03
Identifiers
Aliases	ORC6, ORC6L, origin recognition complex subunit 6
External IDs	MGI: 1929285 HomoloGene: 8635 GeneCards: ORC6
Gene ontology Molecular function • DNA binding • protein binding • DNA replication origin binding Cellular component • nucleus • membrane • nucleoplasm • origin recognition complex • fibrillar center • nuclear origin of replication recognition complex Biological process • G1/S transition of mitotic cell cycle • DNA replication • DNA replication initiation • negative regulation of cell division Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	23594	56452
Ensembl	ENSG00000091651	ENSMUSG00000031697
UniProt	Q9Y5N6	Q9WUJ8
RefSeq (mRNA)	NM_014321	NM_001163791 NM_019716
RefSeq (protein)	NP_055136	n/a
Location (UCSC)	Chr 16: 46.69 – 46.7 Mb	Chr 8: 85.3 – 85.31 Mb
PubMed search

Origin recognition complex subunit 6 (ORC6)
Identifiers
Symbol	ORC6
Pfam	PF05460
InterPro	IPR008721
Available protein structures: Pfam structures PDB RCSB PDB; PDBe; PDBj PDBsum structure summary

Available protein structures:
Pfam	structures
PDB	RCSB PDB; PDBe; PDBj
PDBsum	structure summary

3M03

23594

56452

ENSG00000091651

ENSMUSG00000031697

Q9Y5N6

Q9WUJ8

NM_014321

NM_001163791
NM_019716

NP_055136

n/a

Origin recognition complex subunit 6 is a protein that in humans is encoded by the ORC6 (ORC6L) gene.

The origin recognition complex (ORC) is a highly conserved six subunit protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins.

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Wikipedia