Nykyfor Timofiyovych Kalchenko (Ukrainian: Никифор Тимофійович Кальчекно; 9 February [O.S. 27 January] 1906 – 14 May 1989) was a Ukrainian and Soviet politician, who served as the head of government of Ukrainian SSR (today's equivalent of prime-minister).
Nykyfor Kalchenko was born in a peasant family in a small village in Poltava Oblast, central Ukraine.
Nykyfor Kalchenko was awarded the Hero of Socialist Labour in 1976.