Nathan William MacChesney (1878–1954) was a prominent Chicago lawyer.
Nathan William MacChesney was born in Chicago on June 2, 1878, the son of Alfred Brunson and Henrietta (Milsom) MacChesney. He was educated at California Wesleyan College, receiving a bachelor's degree in 1898. He later attended Stanford University and the Northwestern University School of Law, before receiving an LL.B. from the University of Michigan Law School in 1902. He was admitted to the bar of Illinois in 1902.
After law school, MacChesney founded a Chicago law firm, ultimately known as MacChesney and Becker, where he practiced law for the next five decades. He served in the United States Army during the Spanish–American War (1898). He was instrumental in founding the Journal of Criminal Law and Criminology in 1910. He served as a special assistant attorney general of the United States in 1911, and as a special state's attorney for Illinois in 1912. He was president of the Illinois State Bar Association 1915-16. He again served in the army during World War I, and was thereafter normally referred to as "General MacChesney" by his associates.
He received an LL.M. from Northwestern in 1922. He was general counsel of the National Association of Real Estate Boards in the 1920s.