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NAChRα10

CHRNA10
Identifiers
Aliases CHRNA10
External IDs MGI: 3609260 HomoloGene: 56886 GeneCards: CHRNA10
Targeted by Drug
muscarine
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001303034
NM_001303035
NM_020402

NM_001081424

RefSeq (protein)

NP_001289963
NP_001289964
NP_065135

n/a

Location (UCSC) Chr 11: 3.67 – 3.67 Mb Chr 7: 102.11 – 102.12 Mb
PubMed search

NM_001303034
NM_001303035
NM_020402

NM_001081424

NP_001289963
NP_001289964
NP_065135

n/a

Neuronal acetylcholine receptor subunit alpha-10, also known as nAChRα10 and cholinergic receptor nicotinic alpha 10, is a protein that in humans is encoded by the CHRNA10 gene. The protein encoded by this gene is a subunit of certain nicotinic acetylcholine receptors (nAchR).

This nAchR subunit is required for the normal function of the olivocochlear system which is part of the auditory system. Furthermore, selective block of α9α10 nicotinic acetylcholine receptors by the conotoxin RgIA has been shown to be analgesic in an animal model of nerve injury pain.


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Wikipedia

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