Before humans went into space, several other animals were launched into space, including numerous other primates, so that scientists could investigate the biological effects of space travel. The United States launched flights containing primate cargo primarily between 1948-1961 with one flight in 1969 and one in 1985. France launched two monkey-carrying flights in 1967. The Soviet Union and Russia launched monkeys between 1983 and 1996. Most primates were anesthetized before lift-off. Overall thirty-two monkeys flew in the space program; none flew more than once. Numerous back-up monkeys also went through the programs but never flew. Monkeys and apes from several species were used, including rhesus monkeys, cynomolgus monkeys, squirrel monkeys, pig-tailed macaques, and chimpanzees.
The first ever primate astronaut was Albert, a rhesus monkey, who on June 11, 1948, rode to over 63 km (39 mi) on a V2 rocket. Albert died of suffocation during the flight.
Albert was followed by Albert II who survived the V2 flight but died on impact on June 14, 1949, after a parachute failure. Albert II became the first monkey in space as his flight reached 134 km (83 mi) - past the Kármán line of 100 km taken to designate the beginning of space. Albert III died at 35,000 feet (10.7 km) in an explosion of his V2 on September 16, 1949. Albert IV, on the last monkey V2 flight, died on impact on December 8 that year after another parachute failure. His flight reached 130.6 km. Alberts I, II, and IV were rhesus monkeys while Albert III was a cynomolgus monkey.
Monkeys later flew on Aerobee rockets. On April 18, 1951, a monkey, possibly called Albert V, died due to parachute failure. Yorick, also called Albert VI, along with 11 mouse crewmates, reached 236,000 ft (72 km) and survived the landing, on September 20, 1951, the first monkey to do so (the dogs Dezik and Tsygan had survived a trip to space in July of that year), although he died 2 hours later. Two of the mice also died after recovery; all of the deaths were thought to be related to stress from overheating in the sealed capsule in the New Mexico sun while awaiting the recovery team. Albert VI's flight surpassed the 50 mile boundary the U.S. used for spaceflight but was below the international definition of space. Patricia and Mike, two cynomolgus monkeys, flew on May 21, 1952, and survived, but their flight was only to 26 kilometers.