Missy Mazzoli (born October 27, 1980 in Lansdale, Pennsylvania) is an American composer and pianist living in Brooklyn, New York, who has received critical acclaim for her chamber, orchestral and operatic work. Her first chamber opera Song from the Uproar, based on the life of Swiss explorer Isabelle Eberhardt and featuring a libretto by Royce Vavrek, premiered at New York City venue The Kitchen in March 2012. It was performed again by LA Opera in October 2015. She is the founder and keyboardist for Victoire, an electro-acoustic band dedicated to performing her music. From 2012-2015 she was composer-in-residence at the Opera Company of Philadelphia, in collaboration with Gotham Chamber Opera and Music-Theater Group. Her music is published by G. Schirmer. Mazzoli received a 2015 Foundation for Contemporary Arts Grants to Artists Award.
Mazzoli holds degrees from the Yale School of Music, the Royal Conservatory of the Hague and Boston University. Her teachers include David Lang, Louis Andriessen, Aaron Jay Kernis, Martin Bresnick, Martijn Padding, and John Harbison.
In 2006 Mazzoli taught composition in the Music Department of Yale University, and from 2007 to 2010 was Executive Director of the MATA Festival in New York City, an organization dedicated to promoting the work of young composers.