Otho (/ˈoʊθoʊ/; Latin: Marcus Salvius Otho Caesar Augustus; 28 April 32 – 16 April 69 AD) was Roman emperor for three months, from 15 January to 16 April 69. He was the second emperor of the Year of the Four Emperors.

A member of a noble Etruscan family, Otho was initially a friend and courtier of the young emperor Nero until he was effectively banished to the governorship of the remote province of Lusitania in 58 AD following his wife Poppaea Sabina's affair with Nero. After a period of moderate rule in the province, he allied himself with Galba, the governor of neighbouring Hispania Tarraconensis, during the revolts of 68 AD. Accompanying Galba on his march to Rome, he aspired to succeed the aged emperor, but revolted and murdered Galba on being passed over for the succession.

Inheriting the problem of the rebellion of Vitellius, commander of the army in Germania Inferior, Otho led a sizeable force which met Vitellius' army at the Battle of Bedriacum. After initial fighting resulted in 40,000 casualties, and a retreat of his forces, Otho committed suicide rather than fight on and Vitellius was proclaimed emperor.

Otho belonged to an ancient and noble Etruscan family, descended from the princes of Etruria and settled at Ferentinum (currently Ferento, near Viterbo) in Etruria.

The future emperor appears first as one of the most reckless and extravagant of the young nobles who surrounded Nero. This friendship was brought to an end in 58 AD because of his wife, the noblewoman Poppaea Sabina. Otho introduced his beautiful wife to the emperor upon Poppaea's insistence, who then began an affair that would eventually lead to her premature death. After securely establishing this position as his mistress, she divorced Otho and had the emperor send him away as governor to the remote province of Lusitania (which is now parts of both modern Portugal and Extremadura, Spain).

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