MYBPC3

MYBPC3
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 1GXE, 2AVG, 2K1M, 2MQ0, 2MQ3, 2V6H, 3CX2, 1PD6
Identifiers
Aliases	MYBPC3, CMD1MM, CMH4, FHC, LVNC10, MYBP-C, Myosin binding protein C, cardiac
External IDs	MGI: 102844 HomoloGene: 215 GeneCards: MYBPC3
Gene ontology Molecular function • myosin binding • titin binding • metal ion binding • myosin heavy chain binding • protein binding • identical protein binding • actin binding • ATPase activator activity • structural constituent of muscle • actin filament binding • muscle alpha-actinin binding • structural molecule activity conferring elasticity Cellular component • cytosol • C zone • sarcomere • striated muscle myosin thick filament • myosin filament • A band • Z disc • M band Biological process • regulation of muscle filament sliding • positive regulation of ATPase activity • cardiac muscle contraction • heart morphogenesis • ventricular cardiac muscle tissue morphogenesis • regulation of striated muscle contraction • cell adhesion • muscle filament sliding • striated muscle contraction • actin filament organization • sarcomere organization • striated muscle myosin thick filament assembly Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	4607	17868
Ensembl	ENSG00000134571	ENSMUSG00000002100
UniProt	Q14896	O70468
RefSeq (mRNA)	NM_000256	NM_008653
RefSeq (protein)	NP_000247 NP_000247.2	n/a
Location (UCSC)	Chr 11: 47.33 – 47.35 Mb	Chr 2: 91.12 – 91.14 Mb
PubMed search

1GXE, 2AVG, 2K1M, 2MQ0, 2MQ3, 2V6H, 3CX2, 1PD6

4607

17868

ENSG00000134571

ENSMUSG00000002100

Q14896

O70468

NM_000256

NM_008653

NP_000247
NP_000247.2

n/a

The myosin-binding protein C, cardiac-type is a protein that in humans is encode by the MYBPC3 gene. This isoform is expressed exclusively in heart muscle during human and mouse development, and is distinct from those expressed in slow skeletal muscle (MYBPC1) and fast skeletal muscle (MYBPC2).

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