MTSS1

MTSS1
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 2D1K
Identifiers
Aliases	MTSS1, MIM, MIMA, MIMB, metastasis suppressor 1, I-BAR domain containing
External IDs	MGI: 2384818 HomoloGene: 8841 GeneCards: MTSS1
Gene location (Human) Chr. Chromosome 8 (human) Band 8q24.13 Start 124,550,790 bp End 124,728,429 bp
Gene location (Mouse) Chr. Chromosome 15 (mouse) Band 15|15 D1 Start 58,941,244 bp End 59,082,026 bp
RNA expression pattern More reference expression data
Gene ontology Molecular function • actin monomer binding • protein binding • identical protein binding • actin binding • receptor binding Cellular component • cytoplasm • ruffle • endocytic vesicle • actin cytoskeleton • cytoskeleton Biological process • renal tubule morphogenesis • nephron tubule epithelial cell differentiation • movement of cell or subcellular component • transmembrane receptor protein tyrosine kinase signaling pathway • cellular response to fluid shear stress • cell adhesion • epithelial cell proliferation involved in renal tubule morphogenesis • microspike assembly • negative regulation of epithelial cell proliferation • plasma membrane organization • actin cytoskeleton organization • glomerulus morphogenesis Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	9788	211401
Ensembl	ENSG00000170873	ENSMUSG00000022353
UniProt	O43312	Q8R1S4
RefSeq (mRNA)	NM_001282971 NM_001282974 NM_014751	NM_001146180 NM_144800
RefSeq (protein)	NP_001269900 NP_001269903 NP_055566	NP_001139652 NP_659049
Location (UCSC)	Chr 8: 124.55 – 124.73 Mb	Chr 8: 58.94 – 59.08 Mb
PubMed search

2D1K

9788

211401

ENSG00000170873

ENSMUSG00000022353

O43312

Q8R1S4

NM_001282971
NM_001282974
NM_014751

NM_001146180
NM_144800

NP_001269900
NP_001269903
NP_055566

NP_001139652
NP_659049

Metastasis suppressor protein 1 is a protein that in humans is encoded by the MTSS1 gene. True to its name, it codes for a metastasis suppressor.

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