MOCS3

MOCS3
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 3I2V
Identifiers
Aliases	MOCS3, UBA4, molybdenum cofactor synthesis 3
External IDs	MGI: 1916622 HomoloGene: 6108 GeneCards: MOCS3
Gene ontology Molecular function • transferase activity • nucleotide binding • thiosulfate sulfurtransferase activity • molybdopterin-synthase sulfurtransferase activity • metal ion binding • URM1 activating enzyme activity • protein binding • catalytic activity • small protein activating enzyme activity • ATP binding • molybdopterin-synthase adenylyltransferase activity • nucleotidyltransferase activity • sulfurtransferase activity Cellular component • cytoplasm • cytosol Biological process • molybdopterin cofactor biosynthetic process • tRNA processing • Mo-molybdopterin cofactor biosynthetic process • metabolic process • tRNA wobble uridine modification • enzyme active site formation via cysteine modification to L-cysteine persulfide • tRNA thio-modification • tRNA wobble position uridine thiolation Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	27304	69372
Ensembl	ENSG00000124217	ENSMUSG00000074576
UniProt	O95396	A2BDX3
RefSeq (mRNA)	NM_014484	NM_001160330
RefSeq (protein)	NP_055299	NP_001153802.1 NP_001153802
Location (UCSC)	Chr 20: 50.96 – 50.96 Mb	Chr 2: 168.23 – 168.23 Mb
PubMed search

3I2V

27304

69372

ENSG00000124217

ENSMUSG00000074576

O95396

A2BDX3

NM_014484

NM_001160330

NP_055299

NP_001153802.1
NP_001153802

Adenylyltransferase and sulfurtransferase MOCS3 is an enzyme that in humans is encoded by the MOCS3 gene.

Molybdenum cofactor (MoCo) is necessary for the function of all molybdoenzymes. One of the enzymes required for the biosynthesis of MoCo is molybdopterin synthase (MPT synthase). The protein encoded by this gene adenylates and activates MPT synthase. This gene contains no introns. A pseudogene of this gene is present on chromosome 14.

...
Wikipedia