MAP1LC3A

Available structures

Ortholog search: PDBe RCSB

List of PDB id codes
3ECI, 3WAL, 3WAN, 4ZDV

Identifiers

Aliases

MAP1LC3A, ATG8E, LC3, LC3A, MAP1ALC3, MAP1BLC3, microtubule associated protein 1 light chain 3 alpha

External IDs

MGI: 1915661 HomoloGene: 12021 GeneCards: MAP1LC3A

Gene location (Human)

Chr.	Chromosome 20 (human)

Band	20q11.22	Start	34,546,854 bp
Band	20q11.22	End	34,560,345 bp

Gene location (Mouse)

Chr.	Chromosome 2 (mouse)

Band	2\|2 H1	Start	155,276,297 bp
Band	2\|2 H1	End	155,278,073 bp

Gene ontology
Molecular function	• phosphatidylethanolamine binding • protein binding • phospholipid binding • ubiquitin protein ligase binding
Cellular component	• cytoplasm • organelle membrane • cytosol • late endosome • membrane • autophagosome • microtubule • cytoskeleton • cytoplasmic vesicle • endomembrane system • autolysosome • autophagosome membrane
Biological process	• autophagy • autophagy of mitochondrion • autophagosome assembly • response to iron(II) ion • response to lead ion • response to nutrient levels • cellular response to amino acid starvation • response to morphine • cellular response to hydrogen peroxide • cellular response to copper ion • cellular response to nitrogen starvation • cellular response to starvation • macroautophagy • autophagosome maturation
Sources:Amigo / QuickGO

Orthologs

Species

Human

Mouse

Entrez


84557


66734

Ensembl


ENSG00000101460


ENSMUSG00000027602

UniProt


Q9H492


Q91VR7

RefSeq (mRNA)


NM_032514 NM_181509


NM_025735

RefSeq (protein)


NP_115903 NP_852610


NP_080011

Location (UCSC)

Chr 20: 34.55 – 34.56 Mb

Chr 20: 155.28 – 155.28 Mb

PubMed search

3ECI, 3WAL, 3WAN, 4ZDV

Microtubule-associated proteins 1A/1B light chain 3A is a protein that in humans is encoded by the MAP1LC3A gene. Two transcript variants encoding different isoforms have been found for this gene.

MAP1A and MAP1B are microtubule-associated proteins which mediate the physical interactions between microtubules and components of the cytoskeleton. MAP1A and MAP1B each consist of a heavy chain subunit and multiple light chain subunits. The protein encoded by this gene is one of the light chain subunits and can associate with either MAP1A or MAP1B.

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