Lyons Brook is a Canadian rural community in Pictou County, Nova Scotia.
Located along the West River of Pictou, Lyons Brook is immediately west of the town of Pictou and has several newer subdivisions as well as older homes fronting the river.
The community is located on a former CN Rail line that ran from Oxford Junction to Pictou and on to Stellarton. Rail service was abandoned in 1986 and the tracks were removed in 1989.
Lyons Brook is home to West Pictou Consolidated School and the former childhood home of Canadian grocery titan Frank H. Sobey.
Coordinates: 45°40′15.6″N 62°46′44.2″W / 45.671000°N 62.778944°W