"Lose Yourself to Dance" is a song by French electronic music duo Daft Punk, featuring vocals from American singer Pharrell Williams. The song was written by Daft Punk, Williams, and American musician Nile Rodgers of the disco group Chic, for Daft Punk's fourth studio album Random Access Memories (2013). It appears as the sixth track on the album.

The song was distributed to radio stations as the second single from the album on 13 August 2013, following the worldwide hit single "Get Lucky". Prior to this release, "Lose Yourself to Dance" charted in various countries, including France, Sweden, Switzerland and the United Kingdom. In the UK, it joined the playlists of BBC Radio 1, BBC Radio 2, and a number of commercial and smaller stations. It had reached number 49 in the UK Singles Chart.

"Lose Yourself to Dance" is a disco and funk song in the key of B-flat minor with a tempo of 100 BPM. Daft Punk expressed that the song was the result of a desire to create dance music with live drummers.Thomas Bangalter elaborated that they wished to redefine dance music as "something lighter or something more [primal]", and that the song is meant to evoke the sense of being unified and connected on the dance floor.

Pharrell Williams sings lead vocals on "Lose Yourself to Dance". Williams stated that the song "makes me feel like walking down the street in the middle of the night in London and it's 1984, 1985. I don't hear '70s in that at all." He also believed that David Bowie could theoretically have sung the song. Additional vocals are performed by Daft Punk using vocoders, which Nick DeCosemo of Mixmag felt resembled their 2001 song "Harder, Better, Faster, Stronger". Instrumentalists who perform on "Lose Yourself to Dance" include Nile Rodgers on rhythm guitar, Nathan East on bass guitar, and John "J.R." Robinson on drums. Its "heavy beats" are said to resemble American rock singer Billy Squier's 1980 song "The Big Beat". Jeremy Abbott of Mixmag felt that, "Big multi-layered claps and thrashing cymbals also play a big part in driving the song forward."

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