Liu Wei Di Huang Wan

Liu Wei Di Huang Wan, also known as Liuwei Dihuang teapills (simplified Chinese: 六味地黄丸; traditional Chinese: 六味地黃丸; pinyin: liùwèi dìhuáng wán) or Six Flavor Rehmanni, is a prescription (方剂 fāng jì) in traditional Chinese medicine and pharmacy to treat yin deficiency. In Japanese kampo, it is known as "Rokumi-gan" (六味丸 ろくみがん) (it is also known as Kampo #87). It is commonly made into Chinese patent medicine.

The formula was created by Qian Yi (simplified Chinese: 钱乙; traditional Chinese: 錢乙; pinyin: Qián Yǐ) as dihuang pill (地黄丸). It was published in "Xiao'er Yao Zheng Zhi Jue" (also known as "Key to Therapeutics of Children's Diseases" or "The Correct Execution of Pediatric Medicinals and Patterns" simplified Chinese: 小儿药证直诀; traditional Chinese: 小兒藥證直訣; pinyin: Xiǎo'ér Yào Zhèng Zhí Jué) in 1119 by Qian Yi's student.

The formula was changed slightly when it was borrowed as a Japanese kampo formula. Some Chinese species of herbs were replaced with herbs found in Japan. For example, Alisma plantago-aquatica was replaced with Alisma orientale for zé xiè.

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