Lactitol

Lactitol
Names

IUPAC name 4-O-α-D-Galactopyranosyl-D-glucitol
Other names Lactitol Lacty
Identifiers
CAS Number	585-86-4^Y
3D model (Jmol)	Interactive image
ChEBI	CHEBI:75323^N
ChemSpider	138481^Y
ECHA InfoCard	100.008.698
E number	E966 (glazing agents, ...)
KEGG	D08266^Y
PubChem	157355
UNII	L2B0WJF7ZY^Y
InChI InChI=1S/C12H24O11/c13-1-4(16)7(18)11(5(17)2-14)23-12-10(21)9(20)8(19)6(3-15)22-12/h4-21H,1-3H2/t4-,5+,6+,7+,8-,9-,10+,11+,12-/m0/s1^Y Key: VQHSOMBJVWLPSR-JVCRWLNRSA-N^Y InChI=1/C12H24O11/c13-1-4(16)7(18)11(5(17)2-14)23-12-10(21)9(20)8(19)6(3-15)22-12/h4-21H,1-3H2/t4-,5+,6+,7+,8-,9-,10+,11+,12-/m0/s1 Key: VQHSOMBJVWLPSR-JVCRWLNRBY
SMILES O([C@@H]([C@H](O)[C@@H](O)CO)[C@H](O)CO)[C@@H]1O[C@@H]([C@H](O)[C@H](O)[C@H]1O)CO
Properties
Chemical formula	C₁₂H₂₄O₁₁
Molar mass	344.31 g·mol⁻¹
Melting point	146 °C (295 °F; 419 K)
Pharmacology
ATC code	A06AD12 (WHO)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
N (what is ^YN ?)
Infobox references

Lactitol is a sugar alcohol used as a replacement bulk sweetener for low calorie foods with approximately 40% of the sweetness of sugar. It is also used medically as a laxative. Lactitol is produced by two manufacturers, Danisco and Purac Biochem.

Lactitol is used in a variety of low food energy or low fat foods. High stability makes it popular for baking. It is used in sugar-free candies, cookies (biscuits), chocolate, and ice cream. Lactitol also promotes colon health as a prebiotic. Because of poor absorption, lactitol only has 2.4 Calories (9 kilojoules) per gram, compared to 4 Calories (17 kJ) per gram for typical carbohydrates.

Lactitol is listed as an excipient in some prescription drugs, such as Adderall.

Lactitol is a laxative and is used to prevent or treat constipation, e.g., under the trade name Importal.

Lactitol in combination with Ispaghula husk is an approved combination for idiopathic constipation as a laxative and is used to prevent or treat constipation.

Lactitol, erythritol, sorbitol, xylitol, mannitol, and maltitol are all sugar alcohols. The United States Food and Drug Administration (FDA) classifies sugar alcohols as "generally recognized as safe" (GRAS). They are approved as food additives, and are recognized as not contributing to tooth decay or causing increases in blood glucose. Lactitol is also approved for use in foods in most countries around the world.

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