LDB3

LDB3
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 4YDP
Identifiers
Aliases	LDB3, CMD1C, CMPD3, CYPHER, LDB3Z1, LDB3Z4, LVNC3, MFM4, ORACLE, PDLIM6, ZASP, CMH24, LIM domain binding 3
External IDs	MGI: 1344412 HomoloGene: 134626 GeneCards: LDB3
Gene ontology Molecular function • cytoskeletal protein binding • zinc ion binding • protein binding • metal ion binding • muscle alpha-actinin binding • protein kinase C binding Cellular component • cytoplasm • perinuclear region of cytoplasm • cell projection • pseudopodium • Z disc • cytoskeleton Biological process • sarcomere organization Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	11155	24131
Ensembl	ENSG00000122367	ENSMUSG00000021798
UniProt	O75112	Q9JKS4
RefSeq (mRNA)	NM_001080114 NM_001080115 NM_001080116 NM_001171610 NM_001171611 NM_007078	NM_001039071 NM_001039072 NM_001039073 NM_001039074 NM_001039075 NM_001039076 NM_011918
RefSeq (protein)	NP_001073583 NP_001073584 NP_001073585 NP_001165081 NP_001165082 NP_009009	NP_001034160.1 NP_001034161.1 NP_001034162.1 NP_001034163.1 NP_001034164.1 NP_001034165.1 NP_036048.3 NP_001034160 NP_001034161 NP_001034162 NP_001034163 NP_001034164 NP_001034165 NP_036048
Location (UCSC)	Chr 10: 86.67 – 86.74 Mb	Chr 14: 34.53 – 34.59 Mb
PubMed search

4YDP

11155

24131

ENSG00000122367

ENSMUSG00000021798

O75112

Q9JKS4

NM_007078

NM_001039076
NM_011918

NP_009009

NP_001034165.1
NP_036048.3
NP_001034160
NP_001034161
NP_001034162
NP_001034163
NP_001034164
NP_001034165
NP_036048

LIM domain binding 3 (LDB3), also known as Z-band alternatively spliced PDZ-motif (ZASP), is a protein which in humans is encoded by the LDB3 gene. ZASP belongs to the Enigma subfamily of proteins and stabilizes the sarcomere (the basic units of muscles) during contraction, through interactions with actin in cardiac and skeletal muscles. Mutations in the ZASP gene has been associated with several muscular diseases.

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Wikipedia