LAMB3

LAMB3
Identifiers
Aliases	LAMB3, BM600-125KDA, LAM5, LAMNB1, AI1A, Laminin, beta 3, laminin subunit beta 3
External IDs	MGI: 99915 HomoloGene: 191 GeneCards: LAMB3
Gene ontology Molecular function • protein complex binding • protein binding • structural molecule activity Cellular component • proteinaceous extracellular matrix • extracellular region • basement membrane • laminin-5 complex Biological process • hemidesmosome assembly • cell adhesion • extracellular matrix disassembly • extracellular matrix organization • endodermal cell differentiation • brown fat cell differentiation • epidermis development Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	3914	16780
Ensembl	ENSG00000196878	ENSMUSG00000026639
UniProt	Q13751	Q61087
RefSeq (mRNA)	NM_000228 NM_001017402 NM_001127641	NM_001277928 NM_008484
RefSeq (protein)	NP_000219 NP_001017402 NP_001121113	NP_001264857.1 NP_032510.2 NP_001264857 NP_032510
Location (UCSC)	Chr 1: 209.61 – 209.65 Mb	Chr 1: 193.21 – 193.34 Mb
PubMed search

3914

16780

ENSG00000196878

ENSMUSG00000026639

Q13751

Q61087

NM_000228
NM_001017402
NM_001127641

NM_001277928
NM_008484

NP_000219
NP_001017402
NP_001121113

NP_001264857.1
NP_032510.2
NP_001264857
NP_032510

Laminin subunit beta-3 is a protein that in humans is encoded by the LAMB3 gene.

LAMB3 encodes the beta 3 subunit of laminin. Laminin is composed of three subunits (alpha, beta, and gamma), and refers to a family of basement membrane proteins. For example, LAMB3 serves as the beta chain in laminin-5. Mutations in LAMB3 have been identified as the cause of various types of epidermolysis bullosa. Two alternatively spliced transcript variants encoding the same protein have been found for this gene.

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Wikipedia