L-selectin

SELL
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 2LGF, 3CFW
Identifiers
Aliases	SELL, CD62L, LAM1, LECAM1, LEU8, LNHR, LSEL, LYAM1, PLNHR, TQ1, selectin L
External IDs	MGI: 98279 HomoloGene: 539 GeneCards: SELL
Gene ontology Molecular function • protease binding • heparin binding • protein binding • glycosphingolipid binding • cell adhesion molecule binding • carbohydrate binding Cellular component • integral component of membrane • cell surface • plasma membrane • integral component of plasma membrane • membrane • external side of plasma membrane • secretory granule membrane Biological process • response to ATP • cell adhesion • regulation of immune response • neutrophil degranulation • leukocyte migration Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	6402	20343
Ensembl	ENSG00000188404	ENSMUSG00000026581
UniProt	P14151	P18337
RefSeq (mRNA)	NM_000655	NM_001164059 NM_011346
RefSeq (protein)	NP_000646	NP_035476.1 NP_001157531 NP_035476
Location (UCSC)	Chr 1: 169.69 – 169.71 Mb	Chr 1: 164.06 – 164.08 Mb
PubMed search

2LGF, 3CFW

6402

20343

ENSG00000188404

ENSMUSG00000026581

P14151

P18337

NM_000655

NM_001164059
NM_011346

NP_000646

NP_035476.1
NP_001157531
NP_035476

L-selectin, also known as CD62L, is a cell adhesion molecule found on lymphocytes and the preimplantation embryo. It belongs to the selectin family of proteins, which recognize sialylated carbohydrate groups. It is cleaved by ADAM17.

SELL is a cell surface component that is a member of a family of adhesion/homing receptors that play important roles in lymphocyte-endothelial cell interactions. The molecule is composed of multiple domains: one homologous to lectins, one to epidermal growth factor, and two to the consensus repeat units found in C3/C4-binding proteins.

...
Wikipedia