L-AP4

L-AP4

Identifiers
IUPAC name (2S)-2-amino-4-phosphonobutanoic acid
CAS Number	23052-81-5 Y
PubChem CID	179394
IUPHAR/BPS	1410
ChemSpider	156157 N
ECHA InfoCard	100.164.384
Chemical and physical data
Formula	C4H10NO5P
Molar mass	183.099 g/mol
3D model (Jmol)	Interactive image
SMILES C(CP(=O)(O)O)[C@@H](C(=O)O)N
InChI InChI=1S/C4H10NO5P/c5-3(4(6)7)1-2-11(8,9)10/h3H,1-2,5H2,(H,6,7)(H2,8,9,10)/t3-/m0/s1 N Key:DDOQBQRIEWHWBT-VKHMYHEASA-N N
NY (what is this?)

L-2-amino-4-phosphonobutyric acid (or L-AP4) is a drug used in scientific research, which acts as a group-selective agonist for the group III metabotropic glutamate receptors (mGluR_4/6/7/8). It was the first ligand found to act as an agonist selective for this group of mGlu receptors, but does not show selectivity between the different mGluR Group III subtypes. It is widely used in the study of this receptor family and their various functions.