Khmelnytska oblast (Ukrainian: Хмельницька область, translit. Khmel’nyts’ka oblast’; also referred to as Khmelnychchyna—Ukrainian: Хмельниччина) is an oblast (province) of western Ukraine. The administrative center of the oblast is the city of Khmelnytskyi.

The current estimated population is around 1,401,140 (as of 2004).

Khmelnytska oblast has a total area of 20,600 km² (7,953.70 sq mi) (3.4% of the total area of Ukraine) is located between 48°27' and 50°37' north latitude and between 26°09' and 27°56' east longitude. It is 220 km (136.70 mi) long when measured from north to south, and is 120 km (74.56 mi) in length when measured from east to west. The oblast borders the Rivne Oblast to the northwest, the Zhytomyr Oblast to the northeast, the Vinnytsia Oblast to the east, the Chernivtsi Oblast to the south, and the Ternopil Oblast to the west.

The Podillia highland (270–370 meters above sea-level) occupies the central area of the Khmelnytska oblast. The northwestern areas of the oblast are part of the Volyn highland (highest point — 329 m above sea-level), while to the north, the oblast claims a part of the historic region of Polissia (highest point — 200–250 m above sea-level). The southwestern territory of the Khmelnytska oblast is crossed by the Tovtry range (Ukrainian: Товтровий кряж, translit. Tovtryi kryazh), which includes Mount Velyka Buhaikha (Ukrainian: Велика Бугаїха), the highest point of oblast at 409 m above sea-level. The extreme south of the oblast has a surface with the canyon-like river valleys. The Dneister Reservoir located there is the lowest point of the oblast (121 m above sea-level) .

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