Khmelnytskyi Oblast (Ukrainian: Хмельницька область, translit. Khmel’nyts’ka oblast’; also referred to as Khmelnychchyna—Ukrainian: Хмельниччина) is an oblast (province) of western Ukraine. The administrative center of the oblast is the city of Khmelnytskyi.

The current estimated population is around 1,401,140 (as of 2004).

Khmelnytskyi Oblast has a total area of 20,600 km² (7,953.70 sq mi) (3.4% of the total area of Ukraine) is located between 48°27' and 50°37' north latitude and between 26°09' and 27°56' east longitude. It is 220 km (136.70 mi) long when measured from north to south, and is 120 km (74.56 mi) in length when measured from east to west. It is associated with a historical region of Podolia, yet in reality its territory is split between almost in half northern in Volhynia, southern in Podolia. Its Volhynian region contains smaller cities like Izyaslav, Starokostiantyniv, Shepetivka, while its Podolian portion more developed cities of Khmelnytskyi and Kamianets-Podilskyi.

The oblast borders the Rivne Oblast to the northwest, the Zhytomyr Oblast to the northeast, the Vinnytsia Oblast to the east, the Chernivtsi Oblast to the south, and the Ternopil Oblast to the west.

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