KAT6B

Identifiers

KAT6B, GTPTS, MORF, MOZ2, MYST4, ZC2HC6B, qkf, querkopf, lysine acetyltransferase 6B

External IDs

RNA expression pattern

More reference expression data

Gene ontology
Molecular function	• transferase activity • DNA binding • transferase activity, transferring acyl groups other than amino-acyl groups • protein complex binding • transcription factor binding • metal ion binding • histone acetyltransferase activity • protein binding • acetyltransferase activity • transferase activity, transferring acyl groups
Cellular component	• nucleoplasm • nucleosome • MOZ/MORF histone acetyltransferase complex • nucleus
Biological process	• nucleosome assembly • regulation of transcription, DNA-templated • transcription, DNA-templated • positive regulation of transcription, DNA-templated • histone acetylation • histone H3 acetylation • negative regulation of transcription, DNA-templated • positive regulation of transcription from RNA polymerase II promoter • covalent chromatin modification • cellular response to leukemia inhibitory factor
Sources:Amigo / QuickGO

Orthologs

Species

Human

Mouse

Entrez


23522


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ENSG00000156650 ENSG00000281813


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Q8WYB5


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RefSeq (mRNA)


NM_001256468 NM_001256469 NM_012330


n/a

RefSeq (protein)


NP_001243397 NP_001243398 NP_036462


n/a

Location (UCSC)

n/a

PubMed search

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Histone acetyltransferase MYST4 is an enzyme that in humans is encoded by the MYST4 gene.

MYST4 has been shown to interact with RUNX2.

It has been demonstrated that de novo mutations in the gene MYST4 causes the Young Simpson syndrome and genitopatellar syndrome.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.