John Penry (1559 – 29 May 1593) is Wales's most famous Protestant martyr.
He was born in Brecknockshire, Wales; Cefn Brith, a farm near Llangammarch, is traditionally recognised as his birthplace. He matriculated at Peterhouse, Cambridge, in December 1580, being then probably a Roman Catholic; but soon became a Protestant, with strong Puritan tendencies. Having graduated B.A., he moved to St Alban Hall, Oxford, and gained his M.A. in July 1586. He did not seek ordination, but was licensed as University Preacher.
There is not much evidence for his preaching tours in Wales; they could only have been made during a few months of 1586 or the autumn of 1587. In 1562 an act of parliament had made provision for translating the Bible into Welsh, and the New Testament was issued in 1567; but the number printed would barely supply a copy for each parish church. Indignant at this failure, Penry published, early in 1587, The Æquity of an Humble Supplication "in the behalf of the country of Wales, that some order may be taken for the preaching of the Gospel among those people". Archbishop Whitgift, angry at the implied criticism, had him brought before the High Commission and imprisoned for about a month. On his release Penry married a lady of Northampton, and lived there for some years. With the assistance of Sir Richard Knightley, he set up a printing press, which for nearly a year from Michaelmas 1588 was in active operation. It was successively located at East Moulsey (Surrey), Fawsley (Northamptonshire), Coventry and other places in Warwickshire, and finally at Manchester, where it was seized in August 1589. On it were printed Penry's Exhortation to the governours and people of Wales, and View of... such publike wants and disorders as are in the service of God... in Wales; as well as the celebrated Martin Marprelate tracts.