Jūsō (十三?, lit. "Thirteen") is an area in Yodogawa-ku in north central Osaka, Japan.
The core of the area is Jūsō Station, the hub station of the Hankyu Railway system. The area typifies the unique culture of Osaka. Situated across the Yodo River from central Osaka, Jūsō is centrally located for easy access by Hankyu Railway lines to other major Kansai cities: 24 minutes to Kobe (Kobe-Sannomiya Station) to the west and 40 minutes to Kyoto (Kawaramachi Station) to the northeast.
Predominantly known as the pink area of Osaka, Jūsō has a robust red light district area in the Hommachi West area.
Jūsō is also famous for its wide variety of high quality classic Osaka cuisine featuring okonomiyaki, negiyaki, and takoyaki shops.
In August every year, a massive fireworks celebration takes place beside the Yodo River; the people who attend this celebration often wear traditional yukatas and wooden sandals.
The name Jūsō is written with the kanji for "thirteen." One theory as the origin of the name states that it was originally the thirteenth stop on the Yodo River going from Kyoto to Osaka Bay. A less popular theory holds that the name originated in numbering under the old jorisei (条里制?) land allocation system.