Iowa 22
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| Route information | ||||
| Maintained by Iowa DOT | ||||
| Length: | 97.905 mi (157.563 km) | |||
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| West end: |
 Iowa 21 in Thornburg
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| East end: |
  US 61 Business in Davenport |
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Iowa Highway 22 (Iowa 22) is a 98-mile (158 km) west–east state highway that traverses primarily rural areas in east-central Iowa. The highway begins near Thornburg at an intersection with Iowa Highway 21 and ends in southwestern Davenport, at U.S. Highway 61 Business.
Iowa Highway 22 begins west of Thornburg at Iowa Highway 21. It continues east through Keswick and Webster. Between Webster and South English, Iowa 22 is overlapped with Iowa Highway 149. It continues east from South English through Kinross and Wellman before intersecting Iowa Highway 1 at Kalona. It proceeds east from Kalona to go through Riverside and then intersects U.S. Highway 218 and Iowa Highway 27. After crossing the Iowa River, it goes through Nichols, where a short overlap with Iowa Highway 70 begins. It then continues eastward and intersects U.S. Highway 61 at Muscatine. It goes around the west and north city limits of Muscatine before intersecting Iowa Highway 38 and Business US 61 and turns south into Muscatine. It then turns east along a route next to the Mississippi River and passes through Buffalo before intersecting Interstate 280 at Davenport. It then turns north to end at U.S. 61.
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