Interleukin-9

IL9
Identifiers
Aliases	IL9, HP40, IL-9, P40, interleukin 9
External IDs	OMIM: 146931 MGI: 96563 HomoloGene: 492 GeneCards: IL9
Gene ontology Molecular function • interleukin-9 receptor binding • cytokine activity • growth factor activity • cytokine receptor binding Cellular component • extracellular region • extracellular space Biological process • positive regulation of cell growth • inflammatory response • positive regulation of interleukin-5 biosynthetic process • immune response • positive regulation of cell proliferation Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	3578	16198
Ensembl	ENSG00000145839	ENSMUSG00000021538
UniProt	P15248	P15247
RefSeq (mRNA)	NM_000590	NM_008373
RefSeq (protein)	NP_000581	NP_032399.1 NP_032399
Location (UCSC)	Chr 5: 135.89 – 135.9 Mb	Chr 13: 56.48 – 56.48 Mb
PubMed search

3578

16198

ENSG00000145839

ENSMUSG00000021538

P15248

P15247

NM_000590

NM_008373

NP_000581

NP_032399.1
NP_032399

Interleukin 9, also known as IL-9, is a cytokine (cell signalling molecule) belonging to the group of interleukins.

Il-9 is a cytokine secreted by CD4+ helper cells that acts as a regulator of a variety of hematopoietic cells. This cytokine stimulates cell proliferation and prevents apoptosis. It functions through the interleukin-9 receptor (IL9R), which activates different signal transducer and activator (STAT) proteins and thus connects this cytokine to various biological processes. The gene encoding this cytokine has been identified as a candidate gene for asthma. Genetic studies on a mouse model of asthma demonstrated that this cytokine is a determining factor in the pathogenesis of bronchial hyperresponsiveness.

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Wikipedia