Icie Gertrude Macy Hoobler (July 23, 1892 – January 6, 1984) was an American biochemist who did research in human nutrition, specifically pertaining to mothers and children. Despite facing discrimination because of her gender, she became the first woman chair of a local section of the American Chemical Society and won 22 awards and honors for her laboratory's research.
Hoobler grew up on a farm in Gallatin, Missouri where she became interested in science from watching the maturation of animals and spending time roaming around her family's property. She became especially interested in children's wellness when on a trip during her childhood, where she observed sick children in poor living conditions in the mountains of Arkansas and became aroused with compassion.
Before pursuing a career in chemistry, Hoobler spent three years at the Central Female College in Lexington, Missouri at the urging of her parents, against her own wishes. At Central College, she met her first mentor, biology teacher Lily Egbert, who encouraged her to pursue science. With a new passion for science, she decided to attend the University of Chicago to major in chemistry with a minor in physics. Her advisor at University of Chicago sent her to University of Colorado at Boulder to teach inorganic chemistry.
Hoobler went on to earn her master's degree from the University of Colorado in 1918. Her first master's project was developing a more sensitive cyanide test for autopsies, which resulted in her first publication. Her second project was improving an extraction method for tungstic acid from tungsten ores. Additionally, Hoobler was a teaching assistant in the physiological chemistry course at the medical school.
Immediately after earning her master's degree, she entered a Ph.D. program at Yale University, where she studied physiological chemistry. At the time, Yale admitted a handful of female graduate students, but it was difficult for these female students to find housing near campus, as landlords discriminated against women and saw them as "bothersome." Hoobler joined the Graduate Women's Club and worked to improve living arrangements for female graduate students. Eventually, due to persuasion of the Graduate Women's Club, the university provided an on-campus living option to female students.