Heroin addiction

Opioid use disorder
Synonyms	opioid addiction, problematic opioid use opioid abuse
Classification and external resources
Specialty	psychiatry
ICD-10	F11.2
ICD-9-CM	304.0
MeSH	D009293
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Opioid use disorder is a medical condition characterized by a problematic pattern of opioid use that causes clinically significant impairment or distress. It often includes a strong desire to use opioids, increased tolerance to opioids, and withdrawal syndrome when opioids are abruptly discontinued.Addiction and dependence are components of a substance use disorder and addiction represents the most severe form of the disorder. Opioid dependence can manifest as physical dependence, psychological dependence, or both.

Opioids include substances such as morphine, heroin, codeine and oxycodone. These can be bought illegally or prescribed. The diagnosis of opioid use disorder is often based on criteria by the American Psychiatric Association in the DSM-5. These include a preoccupation with a desire to obtain and take opioids, as well as using more than intended despite social and professional consequences due to these behaviors.

Opioid use disorder can be treated with opioid replacement therapy using methadone or buprenorphine. Additionally, individuals with opioid use disorder may benefit from twelve-step programs and support from mental health professionals such as individual or group therapy.Naloxone is useful for the treatment of opioid overdose.

Opioid use disorders affects about 0.4% of people in a given year. About 16 million people have been affected at one point in time. It resulted in 122,000 deaths worldwide in 2015, up from 18,000 deaths in 1990. In the United States in 2015 there were 33,000 deaths due to drug overdose involving opioids. Of those 33,000 deaths, about 15,000 were from prescribed opioids and 13,000 from heroin.

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