Gualdo Tadino Cathedral (Italian: Duomo di Gualdo Tadino; Basilica Cattedrale di San Benedetto) is a Roman Catholic cathedral in Gualdo Tadino in Umbria, Italy, dedicated to Saint Benedict of Nursia. Formerly a Benedictine abbey church, it became a cathedral in 1915, and is now a co-cathedral in the diocese of Assisi-Nocera Umbra-Gualdo Tadino.
In January 1980 Pope John Paul II granted it the honour of the status of a minor basilica.
The present cathedral is also known as "San Benedetto nuovo" ("new St. Benedict's") to distinguish it from another building, "San Benedetto vecchio" ("old St. Benedict's"), a monastery constructed by the Benedictines after 1006 outside the city walls. Because of the insecurity of the location the monks moved the monastery inside the walls in 1256, as is recorded in a stone inscription on the outside wall of the building: A.D. MCCLVI TPE G ABBATIS H CENOBIU E TRASLATU IN GUALDO ("In A.D. 1256 in the time of Abbot G. this monastery was moved into Gualdo").
The new abbey and the adjoining church were built in a mixture of the Romanesque and Gothic styles, but were refurbished further during the following centuries, particularly in the 18th and 19th centuries: the interior was completely refitted in the 19th century by the architect Virgilio Vespignani. The greater part of the painted decoration originates from 1924 and is the work of Ulisse Ribustini. On the death of Virginio Vespignani, the wors wser continued by his son Francesco and by the architect Costantino Sneider, his assistant, as is recorded in a stone by the entrance to the campanile.