Granulocyte macrophage colony-stimulating factor receptor

CSF2RA

Available structures

Ortholog search: PDBe RCSB

List of PDB id codes
4NKQ, 4RS1

Identifiers

Aliases

CSF2RA, CD116, CDw116, CSF2R, CSF2RAX, CSF2RAY, CSF2RX, CSF2RY, GM-CSF-R-alpha, GMCSFR, GMR, SMDP4, colony stimulating factor 2 receptor alpha subunit

External IDs

OMIM: 425000 MGI: 1339754 HomoloGene: 48406 GeneCards: CSF2RA

Gene ontology
Molecular function	• protein binding • cytokine receptor activity • receptor activity • protein tyrosine kinase activity • Ras guanyl-nucleotide exchange factor activity
Cellular component	• integral component of membrane • membrane • plasma membrane • integral component of plasma membrane • extracellular region • intracellular
Biological process	• cellular protein metabolic process • MAPK cascade • cytokine-mediated signaling pathway • peptidyl-tyrosine phosphorylation • positive regulation of GTPase activity
Sources:Amigo / QuickGO

RNA expression pattern

More reference expression data

Orthologs

Species

Human

Mouse

Entrez


1438


12982

Ensembl


ENSG00000198223


ENSMUSG00000059326

UniProt


P15509


Q00941

RefSeq (mRNA)

NM_001161529 NM_001161530 NM_001161531 NM_001161532 NM_006140
NM_172245 NM_172246 NM_172247 NM_172248 NM_172249


NM_009970

RefSeq (protein)

NP_001155001 NP_001155002 NP_001155003 NP_001155004 NP_006131
NP_758448 NP_758449 NP_758450 NP_758452


NP_034100.2 NP_034100

Location (UCSC)

Chr X: 1.27 – 1.31 Mb

Chr 19: 61.22 – 61.23 Mb

PubMed search

NM_172245
NM_172246
NM_172247
NM_172248
NM_172249

NM_009970

NP_758448
NP_758449
NP_758450
NP_758452

NP_034100.2
NP_034100

The granulocyte macrophage colony-stimulating factor receptor also known as CD116 (Cluster of Differentiation 116), is a receptor for granulocyte macrophage colony-stimulating factor, which stimulates the production of white blood cells. The receptor is normally located on myeloblast, mature neutrophil, but not on any erythroid or megakaryocytic lineage cells.

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