Grand Tower Island is a river island in the Mississippi River in the midwestern United States, within the state of Missouri on its border with the state of Illinois. Formed within recorded history by the movement of the river, it consists of a bulge-shaped piece of land between the river's primary channel and an oxbow lake. Land on the island is generally valuable for farming, especially when protected from flooding, while the lake has developed a reputation as a valuable sport-fishing location.
Grand Tower Island lies on the left bank of the Mississippi River in a remote area between St. Louis, Missouri and Cairo, Illinois. It shares its name with the adjacent small city of Grand Tower, Illinois, as well as with the landmark Tower Rock island on the Missouri side of the river. Despite its location on the eastern side of the river and its road connections to Illinois, the island is part of Brazeau Township, Perry County, Missouri, in a situation analogous to the right-bank river village of Kaskaskia, Illinois. A towhead (a narrow island much longer than its width) approximately 1 mile (1.6 km) long lies in the river between Grand Tower Island and the Missouri mainland.
The island's location on the "wrong" side of the Mississippi is the result of a cutoff that formed in recorded history: during the early years of steamboat navigation on the river, the main course flowed through a meander, but the course ultimately shifted and converted the meander into a stagnant oxbow lake. Some parts of the lake are susceptible to disappearing via evaporation, although the lake occasionally reconnects with the river for short periods of time; its water normally trickles into the nearby Big Muddy River, which flows into the Mississippi nearby. Measuring approximately 2 miles (3.2 km) east-west and 2.75 miles (4.43 km) north-south, Grand Tower Island is traversed by a single north-south road, Island Road, that travels south from Grand Tower, crosses the island, turns sharply eastward to run along the narrow strip of land between the lake and the lowest section of the Big Muddy River, and then proceeds southeastward to connect with Illinois Route 3. Road access to the rest of Perry County requires a one-way trip of more than 30 miles (48 km) via the Chester Bridge at Chester.