Coordinates: 37°26′55″N 89°38′19″W / 37.44861°N 89.63861°W Fruitland is an unincorporated community in Cape Girardeau County, Missouri, United States. It is located on U.S. Route 61 5 mi (8.0 km) north of Jackson and just northeast of the intersection of US. Route 61 and Interstate 55.
Fruitland is part of the Cape Girardeau–Jackson, MO-IL Metropolitan Statistical Area.
A post office called Fruitland was established in 1886, and remained in operation until 1968. The community was named for a fruit orchard near the original town site.