Fordyce spots

Fordyce spots (also termed Fordyce granules or Fordyce disease) are visible sebaceous glands that are present in most individuals. They appear on the genitals and/or on the face and in the mouth. They appear as small, painless, raised, pale, red or white spots or bumps 1 to 3 mm in diameter that may appear on the scrotum, shaft of the penis or on the labia, as well as the inner surface (retromolar mucosa) and vermilion border of the lips of the face. They are not associated with any disease or illness, nor are they infectious but rather they represent a natural occurrence on the body. No treatment is therefore required, unless the individual has cosmetic concerns. Persons with this condition sometimes consult a dermatologist because they are worried they may have a sexually transmitted disease (especially genital warts) or some form of cancer.

Sebaceous glands are normal adnexal structures of the dermis but may also be found ectopically within the mouth, where they are referred to as Oral Fordyce Granules or ectopic sebaceous glands. On the foreskin they are called Tyson's glands, not to be confused with hirsuties coronae glandis.

When they appear on the penis, they are also called penile sebaceous glands.

When seen as a streak of individual glands along the interface between the skin of the lip and the vermilion border, the terms Fox–Fordyce disease and Fordyce's condition have been used.

On the shaft of the penis, Fordyce spots are more visible when the skin is stretched, and may only be noticeable during an erection. The spots can also appear on the skin of the scrotum.

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