Factor VIII

F8
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 1CFG, 1D7P, 1IQD, 2R7E, 3CDZ, 3HNB, 3HNY, 3HOB, 4BDV, 1FAC, 3J2Q, 3J2S, 4KI5, 4PT6, 4XZU
Identifiers
Aliases	F8, AHF, DXS1253E, F8B, F8C, FVIII, HEMA, coagulation factor VIII
External IDs	OMIM: 300841 MGI: 88383 HomoloGene: 49153 GeneCards: F8
Genetically Related Diseases
vasculitis
Gene ontology Molecular function • metal ion binding • protein binding • oxidoreductase activity • copper ion binding • serine-type endopeptidase activity Cellular component • endoplasmic reticulum lumen • plasma membrane • extracellular region • ER to Golgi transport vesicle • endoplasmic reticulum-Golgi intermediate compartment membrane • platelet alpha granule lumen • Golgi membrane • extracellular space Biological process • hemostasis • platelet degranulation • blood coagulation • ER to Golgi vesicle-mediated transport • COPII vesicle coating • acute-phase response • oxidation-reduction process • blood coagulation, intrinsic pathway • platelet activation • proteolysis Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	2157	14069
Ensembl	ENSG00000185010	ENSMUSG00000031196
UniProt	P00451	Q06194
RefSeq (mRNA)	NM_000132 NM_019863	NM_001161373 NM_001161374 NM_007977
RefSeq (protein)	NP_000123 NP_063916	NP_032003.2 NP_001154845 NP_001154846 NP_032003
Location (UCSC)	Chr X: 154.84 – 155.03 Mb	Chr X: 75.17 – 75.38 Mb
PubMed search

1CFG, 1D7P, 1IQD, 2R7E, 3CDZ, 3HNB, 3HNY, 3HOB, 4BDV, 1FAC, 3J2Q, 3J2S, 4KI5, 4PT6, 4XZU

2157

14069

ENSG00000185010

ENSMUSG00000031196

P00451

Q06194

NM_000132
NM_019863

NM_001161373
NM_001161374
NM_007977

...
Wikipedia