FUBP1

FUBP1
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 1J4W, 2KXH, 4LIJ
Identifiers
Aliases	FUBP1, FBP, FUBP, hDH V, far upstream element binding protein 1
External IDs	MGI: 1196294 HomoloGene: 48253 GeneCards: FUBP1
Gene ontology Molecular function • protein binding • nucleic acid binding • single-stranded DNA binding • transcription factor activity, sequence-specific DNA binding • DNA binding • RNA binding Cellular component • nucleus Biological process • positive regulation of gene expression • regulation of transcription, DNA-templated • transcription from RNA polymerase II promoter • transcription, DNA-templated Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	8880	51886
Ensembl	ENSG00000162613	ENSMUSG00000028034
UniProt	Q96AE4	Q91WJ8
RefSeq (mRNA)	NM_001303433 NM_003902	NM_057172
RefSeq (protein)	NP_001290362 NP_003893	NP_476513
Location (UCSC)	Chr 1: 77.94 – 77.98 Mb	Chr 3: 152.21 – 152.24 Mb
PubMed search

1J4W, 2KXH, 4LIJ

8880

51886

ENSG00000162613

ENSMUSG00000028034

Q96AE4

Q91WJ8

NM_001303433
NM_003902

NM_057172

NP_001290362
NP_003893

NP_476513

Far upstream element-binding protein 1 is a protein that in humans is encoded by the FUBP1 gene.

This gene encodes a ssDNA binding protein that activates the far upstream element (FUSE) of c-myc and stimulates expression of c-myc in undifferentiated cells. Regulation of FUSE by FUBP occurs through single-strand binding of FUBP to the non-coding strand. This protein has been shown to function as an ATP-dependent DNA helicase.

Far upstream element-binding protein 1 has been shown to interact with MAPK14 and SMN1.

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Wikipedia