FSCN1

FSCN1
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 1DFC, 4GP0, 4GP3, 3P53, 4GOY, 4GOV, 3LLP
Identifiers
Aliases	FSCN1, FAN1, HSN, SNL, p55, fascin actin-bundling protein 1
External IDs	MGI: 1352745 HomoloGene: 48164 GeneCards: FSCN1
Gene ontology Molecular function • protein binding, bridging • actin filament binding • protein binding • drug binding • actin binding • RNA binding • cadherin binding Cellular component • cytoplasm • cell projection • cell-cell junction • filopodium • ruffle • myelin sheath • stress fiber • microvillus • cell junction • invadopodium • microspike • cell projection membrane • actin cytoskeleton • podosome • extracellular exosome • cytoskeleton • growth cone • lamellipodium • filamentous actin • cytosol Biological process • regulation of microvillus assembly • establishment of apical/basal cell polarity • regulation of actin cytoskeleton organization • actin filament organization • cell motility • positive regulation of podosome assembly • actin filament bundle assembly • positive regulation of extracellular matrix disassembly • cell-cell junction assembly • microspike assembly • cell proliferation • positive regulation of lamellipodium assembly • cell migration • positive regulation of filopodium assembly • actin cytoskeleton organization • anatomical structure morphogenesis Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	6624	14086
Ensembl	ENSG00000075618	ENSMUSG00000029581
UniProt	Q16658	Q61553
RefSeq (mRNA)	NM_003088	NM_007984
RefSeq (protein)	NP_003079	NP_032010.2 NP_032010
Location (UCSC)	Chr 7: 5.59 – 5.61 Mb	Chr 5: 142.96 – 142.97 Mb
PubMed search

1DFC, 4GP0, 4GP3, 3P53, 4GOY, 4GOV, 3LLP

6624

14086

ENSG00000075618

ENSMUSG00000029581

Q16658

Q61553

NM_003088

NM_007984

NP_003079

NP_032010.2
NP_032010

Fascin is a protein that in humans is encoded by the FSCN1 gene.

FSCN1 has been shown to interact with Low affinity nerve growth factor receptor and PKC alpha.

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Wikipedia