FRAS1

FRAS1
Identifiers
Aliases	FRAS1, Fraser extracellular matrix complex subunit 1
External IDs	MGI: 2385368 HomoloGene: 23516 GeneCards: FRAS1
Gene location (Human) Chr. Chromosome 4 (human) Band n/a Start 78,057,570 bp End 78,544,269 bp
Gene location (Mouse) Chr. Chromosome 5 (mouse) Band n/a Start 96,373,955 bp End 96,784,728 bp
Gene ontology Molecular function • metal ion binding Cellular component • plasma • extracellular matrix • membrane • basement membrane • integral component of membrane • sublamina densa Biological process • skin development • embryonic limb morphogenesis • protein transport • metanephros morphogenesis • morphogenesis of an epithelium • palate development • cell communication Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	80144	231470
Ensembl	ENSG00000138759	ENSMUSG00000034687
UniProt	Q86XX4	Q80T14
RefSeq (mRNA)	NM_001166133 NM_020875 NM_025074 NM_032863 NM_206841	NM_175473
RefSeq (protein)	NP_001159605 NP_079350	NP_780682
Location (UCSC)	Chr 4: 78.06 – 78.54 Mb	Chr 4: 96.37 – 96.78 Mb
PubMed search

80144

231470

ENSG00000138759

ENSMUSG00000034687

Q86XX4

Q80T14

NM_001166133
NM_020875
NM_025074
NM_032863
NM_206841

NM_175473

NP_001159605
NP_079350

NP_780682

Extracellular matrix protein FRAS1 is a protein that in humans is encoded by the FRAS1 (Fraser syndrome 1) gene. This gene encodes an extracellular matrix protein that appears to function in the regulation of epidermal-basement membrane adhesion and organogenesis during development.

Mutations in this gene is observed to cause fraser syndrome.

...
Wikipedia