Erhard Fernholz
| Erhard Fernholz | |
|---|---|
 |
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| Born | Friedrich August Erhard Fernholz June 9, 1909 Hiddenhausen, Germany |
| Died | December 14, 1940 Princeton, New Jersey |
| Nationality | German |
| Fields |
Organic chemistry biochemistry |
| Alma mater | University of Göttingen |
| Doctoral advisor | Adolf Windaus |
| Spouse | Mary Briganti (1938-1940) |
| Children | E. Robert |
Erhard Fernholz (born Friedrich August Erhard Fernholz on June 9, 1909 in Hiddenhausen, Westphalia (Germany) died December 14, 1940 in Princeton, New Jersey (USA)) was a German chemist and investigator of sterols and bile acids.
Erhard Fernholz was the eldest son of Gustav Fernholz and Elisabeth Schwagmeyer, both school teachers in Hiddenhausen where Gustav was also the principal of the local school. Erhard had two younger siblings, Maria Elisabeth and Gustav Johannes Hans, both of whom were also chemists. Erhard Fernholz graduated from the Realgimnasium in 1928 and continued his studies at the University of Göttingen where in 1932, at age 23, he received his PhD degree with highest honors in Chemistry from the Faculty of Mathematics and Natural Sciences. The following year he continued research with his thesis advisor Adolf Windaus and was named university assistant in the Chemistry faculty at Göttingen in charge of the Biochemical Department of the Organic Chemistry Laboratory.
Due to his opposition to Nazism, Fernholz left Germany for the United States in 1935 by virtue of a fellowship he had received from Princeton University to work in the Chemistry Department with Prof. E. S. Wallis. During his brief career, Fernholz contributed more than forty papers to the chemical literature and established himself at an early age as an outstanding investigator. His research was mainly concentrated on sterols and bile acids, and his work on stigma-sterol contributed to the first partial synthesis of progesterone.
After a year at Princeton University, Fernholz joined the research group at Merck & Co., and in 1937 he reported the isolation of durohydroquinone from the thermal decomposition products of , the most active principle of Vitamin E. This research was followed by the complete structure of α-tocopherol that Fernholz presented in 1938, based almost entirely on the basis of his own experiments. That same year Fernholz became head of the division of Organic Chemistry of the newly founded Squibb Institute for Medical Research. In addition to his research contributions in the sterol area, he explored the anti-hemorrhagic properties of natural substances including pioneering work on Vitamin K.
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