Eastern Ukraine or East Ukraine (Ukrainian: Східна Україна, Skhidna Ukrayina; Russian: Восточная Украина, Vostochnaya Ukraina) generally refers to territories of Ukraine east of the Dnieper river, particularly Kharkiv, Luhansk and Donetsk oblasts. Dnipropetrovsk and Zaporizhia Oblasts sometimes are also regarded as Eastern Ukraine. In regard to traditional territories the area encompasses portions of the southern Sloboda Ukraine, Donbas, the western Azov Littoral (Pryazovia).
Almost a third of the country's population lives within the region, which includes several cities with population of around a million. Within Ukraine, the region is the most highly urbanized, particularly portions of central Kharkiv Oblast, south-western Luhansk Oblast, central, northern and eastern areas of Donetsk Oblast.
The region stretches from southern areas of the Central Russian Upland to the northern shores of the Sea of Azov, from the eastern border with Russia to Black Sea and Dnieper lowlands (including the left banks of Dnieper) to the west. Aside of Dnieper, the major river of eastern Ukraine is Seversky Donets which gave the name to the main economical region for that portion of the country, Donbas (Donets basin).