EPHA4

EPHA4
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 2LW8, 2WO1, 2WO2, 2WO3, 3CKH, 3GXU, 4BK4, 4BK5, 4BKA, 4BKF, 4M4P, 4M4R, 4W4Z, 4W50, 5JR2
Identifiers
Aliases	EPHA4, Epha4, 2900005C20Rik, AI385584, Cek8, Hek8, Sek, Sek1, Tyro1, rb, EPH receptor A4, HEK8, SEK, TYRO1
External IDs	MGI: 98277 HomoloGene: 20933 GeneCards: EPHA4
Gene location (Human) Chr. Chromosome 2 (human) Band 2q36.1 Start 221,418,027 bp End 221,574,202 bp
Gene location (Mouse) Chr. Chromosome 1 (mouse) Band 1 C4|1 39.55 cM Start 77,367,185 bp End 77,515,088 bp
RNA expression pattern More reference expression data
Gene ontology Molecular function • transferase activity • protein kinase activity • nucleotide binding • GPI-linked ephrin receptor activity • ephrin receptor binding • DH domain binding • transmembrane-ephrin receptor activity • kinase activity • protein binding • identical protein binding • transmembrane receptor protein tyrosine kinase activity • PH domain binding • protein tyrosine kinase activity • ATP binding • ephrin receptor activity Cellular component • cytoplasm • axon terminus • integral component of membrane • cell body • perikaryon • postsynaptic membrane • Golgi apparatus • endosome • cell projection • early endosome membrane • membrane • postsynaptic density • filopodium • neuromuscular junction • plasma membrane • dendritic spine • axonal growth cone • integral component of plasma membrane • synapse • cell surface • mitochondrial outer membrane • cell junction • axon • dendrite • early endosome • endoplasmic reticulum Biological process • negative regulation of axon regeneration • fasciculation of motor neuron axon • phosphorylation • transmembrane receptor protein tyrosine kinase signaling pathway • positive regulation of JUN kinase activity • regulation of GTPase activity • nervous system development • regulation of axonogenesis • multicellular organism development • protein phosphorylation • regulation of astrocyte differentiation • cell adhesion • positive regulation of dendrite morphogenesis • nephric duct morphogenesis • protein autophosphorylation • corticospinal tract morphogenesis • peptidyl-tyrosine phosphorylation • fasciculation of sensory neuron axon • motor neuron axon guidance • positive regulation of Rho guanyl-nucleotide exchange factor activity • regulation of dendritic spine morphogenesis • glial cell migration • adult walking behavior • axon guidance • ephrin receptor signaling pathway Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	2043	13838
Ensembl	ENSG00000116106	ENSMUSG00000026235
UniProt	P54764	Q03137
RefSeq (mRNA)	NM_001304536 NM_001304537 NM_004438	NM_007936
RefSeq (protein)	NP_001291465 NP_001291466 NP_004429	NP_031962
Location (UCSC)	Chr 2: 221.42 – 221.57 Mb	Chr 2: 77.37 – 77.52 Mb
PubMed search

2LW8, 2WO1, 2WO2, 2WO3, 3CKH, 3GXU, 4BK4, 4BK5, 4BKA, 4BKF, 4M4P, 4M4R, 4W4Z, 4W50, 5JR2

2043

13838

ENSG00000116106

ENSMUSG00000026235

P54764

Q03137

NM_001304536
NM_001304537
NM_004438

...
Wikipedia