EIF2B5

EIF2B5
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 3JUI
Identifiers
Aliases	EIF2B5, CACH, CLE, EIF-2B, EIF2Bepsilon, LVWM, eukaryotic translation initiation factor 2B subunit epsilon
External IDs	MGI: 2446176 HomoloGene: 2903 GeneCards: EIF2B5
Gene ontology Molecular function • translation initiation factor activity • guanyl-nucleotide exchange factor activity • protein binding • translation initiation factor binding Cellular component • cytoplasm • eukaryotic translation initiation factor 2B complex • nucleus • cytosol Biological process • astrocyte development • aging • response to peptide hormone • response to heat • response to glucose • response to endoplasmic reticulum stress • positive regulation of GTPase activity • cellular response to drug • astrocyte differentiation • ovarian follicle development • myelination • oligodendrocyte development • positive regulation of translational initiation • hippocampus development • translational initiation • response to lithium ion • translation • positive regulation of apoptotic process • positive regulation of translation • negative regulation of translational initiation in response to stress Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	8893	224045
Ensembl	ENSG00000145191	ENSMUSG00000003235
UniProt	Q13144	Q8CHW4
RefSeq (mRNA)	NM_003907	NM_172265
RefSeq (protein)	NP_003898	NP_758469.1 NP_758469
Location (UCSC)	Chr 3: 184.14 – 184.15 Mb	Chr 16: 20.5 – 20.51 Mb
PubMed search

3JUI

8893

224045

ENSG00000145191

ENSMUSG00000003235

Q13144

Q8CHW4

NM_003907

NM_172265

NP_003898

NP_758469.1
NP_758469

Translation initiation factor eIF-2B subunit epsilon is a protein that in humans is encoded by the EIF2B5 gene.

EIF2B5 has been shown to interact with EIF2B2 and EIF2B1.

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Wikipedia