Drostanolone propionate

Drostanolone propionate

Clinical data
Trade names	Masteron, Drolban, Masteril, Mastisol, Metormon, Permastril
Pregnancy category	X
Routes of administration	Intramuscular injection or transdermal cream
ATC code	A14
Legal status
Legal status	CA: Schedule IV US: Schedule III
Pharmacokinetic data
Bioavailability	Oral: 0–2% Intramuscular: 100%
Protein binding	Highly
Metabolism	Hepatic
Biological half-life	2–3 Days
Excretion	Renal
Identifiers
IUPAC name (2R,5S,8R,9S,10S,13S,14S,17S)-17-hydroxy-2,10,13-trimethyl-1,2,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-3-one
CAS Number	58-19-5 Y
PubChem CID	224004
IUPHAR/BPS	6947
DrugBank	DB00858 Y
ChemSpider	194604 Y
ChEBI	CHEBI:31523 Y
ECHA InfoCard	100.007.550
Chemical and physical data
Formula	C23H36O3
Molar mass	360.53 g/mol
3D model (Jmol)	Interactive image
SMILES CCC(=O)O[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CC[C@@H]4[C@@]3(C[C@H](C(=O)C4)C)C)C
InChI InChI=1S/C23H36O3/c1-5-21(25)26-20-9-8-17-16-7-6-15-12-19(24)14(2)13-23(15,4)18(16)10-11-22(17,20)3/h14-18,20H,5-13H2,1-4H3/t14-,15+,16+,17+,18+,20+,22+,23+/m1/s1 Y Key:NOTIQUSPUUHHEH-UXOVVSIBSA-N Y

Drostanolone propionate (BAN) (brand names Masteron, Drolban, others), also known as dromostanolone propionate (USAN), as well as 2α-methyl-4,5α-dihydrotestosterone, is a synthetic anabolic-androgenic steroid (AAS) and the propionate ester of drostanolone. It is incapable of aromatization and has similar properties to dihydrotestosterone (DHT). It has been successfully used to treat breast cancer, but because of the high risk of virilization, options with better tolerability are usually prescribed instead. Drostanolone propionate is not orally active, and must be administered instead via intramuscular injection.