Aromatase

CYP19A1

Available structures

Ortholog search: PDBe RCSB

List of PDB id codes
3EQM, 3S79, 3S7S, 4GL5, 4GL7, 4KQ8

Identifiers

CYP19A1, ARO, ARO1, CPV1, CYAR, CYP19, CYPXIX, P-450AROM, cytochrome P450 family 19 subfamily A member 1

External IDs

Targeted by Drug

Gene ontology
Molecular function	• iron ion binding • oxygen binding • metal ion binding • monooxygenase activity • heme binding • oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen • electron carrier activity • oxidoreductase activity • aromatase activity • oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen • steroid hydroxylase activity
Cellular component	• endoplasmic reticulum membrane • endoplasmic reticulum • membrane • integral component of membrane
Biological process	• estrogen biosynthetic process • androgen metabolic process • negative regulation of chronic inflammatory response • prostate gland growth • sterol metabolic process • oxidation-reduction process • negative regulation of macrophage chemotaxis • steroid biosynthetic process • female gonad development • female genitalia development • mammary gland development • uterus development • testosterone biosynthetic process
Sources:Amigo / QuickGO

Orthologs

Species

Human

Mouse

Entrez


1588


13075


ENSG00000137869


ENSMUSG00000032274


P11511


P28649

RefSeq (mRNA)


NM_000103 NM_031226


NM_007810 NM_001348171 NM_001348172 NM_001348173

RefSeq (protein)

NP_000094 NP_001334177 NP_001334178 NP_001334179 NP_001334180
NP_001334181 NP_001334182 NP_001334183 NP_001334184 NP_001334185 NP_112503


NP_031836.1 NP_001335100 NP_001335101 NP_001335102 NP_031836

Location (UCSC)

PubMed search