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Dopamine receptor D1

DRD1
Available structures
PDB Ortholog search: PDBe RCSB
Identifiers
Aliases DRD1, dopamine receptor D1, DADR, DRD1A
External IDs MGI: 99578 HomoloGene: 30992 GeneCards: DRD1
RNA expression pattern
PBB GE DRD1 214652 at fs.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_000794

NM_001291801
NM_010076

RefSeq (protein)

NP_000785

NP_001278730.1
NP_034206.1
NP_001278730
NP_034206

Location (UCSC) Chr 5: 175.44 – 175.44 Mb Chr 13: 54.05 – 54.06 Mb
PubMed search

1OZ5

NM_000794

NM_001291801
NM_010076

NP_000785

NP_001278730.1
NP_034206.1
NP_001278730
NP_034206

Dopamine receptor D1, also known as DRD1, is a protein that in humans is encoded by the DRD1 gene.

The D1 subtype of the dopamine receptor is the most abundant dopamine receptor in the central nervous system. This G-protein coupled receptor is Gs/a coupled and indirectly activates cyclic AMP-dependent protein kinase, stimulating the neuron. D1 receptors regulate neuronal growth and development, mediate some behavioral responses, and modulate dopamine receptor D2-mediated events. Alternative transcription initiation sites result in two transcript variants of the gene.D1-D2 dopamine receptor heteromer formation is observed.


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Wikipedia

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