NP_001278730.1
NP_034206.1
NP_001278730
NP_034206
Dopamine receptor D1, also known as DRD1, is a protein that in humans is encoded by the DRD1 gene.
The D1 subtype of the dopamine receptor is the most abundant dopamine receptor in the central nervous system. This G-protein coupled receptor is Gs/a coupled and indirectly activates cyclic AMP-dependent protein kinase, stimulating the neuron. D1 receptors regulate neuronal growth and development, mediate some behavioral responses, and modulate dopamine receptor D2-mediated events. Alternative transcription initiation sites result in two transcript variants of the gene.D1-D2 dopamine receptor heteromer formation is observed.