DEAE

Diethylethanolamine

Names
IUPAC name 2-(Diethylamino)ethanol
Other names Diethylaminoethanol 2-Diethylaminoethanol N,N-Diethyl-2-aminoethanol N,N-Diethylethanolamine Diethyl(2-hydroxyethyl)amine (2-Hydroxyethyl)diethylamine 2-Diethylaminoethyl alcohol 2-Hydroxytriethylamine
Identifiers
CAS Number	100-37-8 Y
3D model (Jmol)	Interactive image
Beilstein Reference	741863
ChEBI	CHEBI:52153 Y
ChemSpider	13842001 Y
ECHA InfoCard	100.002.587
EC Number	202-845-2
MeSH	2-diethylaminoethanol
PubChem CID	7497
RTECS number	KK5075000
UNII	S6DL4M053U Y
UN number	2686
InChI InChI=1S/C6H15NO/c1-3-7(4-2)5-6-8/h8H,3-6H2,1-2H3 Y Key: BFSVOASYOCHEOV-UHFFFAOYSA-N Y
SMILES CCN(CC)CCO
Properties
Chemical formula	C6H15NO
Molar mass	117.19 g·mol−1
Appearance	Colourless liquid
Odor	Ammoniacal
Density	884 mg mL−1
Melting point	−70 °C; −94 °F; 203 K
Boiling point	161.1 °C; 321.9 °F; 434.2 K
Solubility in water	miscible
log P	0.769
Vapor pressure	100 Pa (at 20 °C)
Refractive index (nD)	1.441–1.442
Hazards
GHS pictograms
GHS signal word	DANGER
GHS hazard statements	H226, H302, H312, H314, H317, H332
GHS precautionary statements	P280, P305+351+338, P310
EU classification (DSD)	C
R-phrases	R10, R20/21/22, R34
S-phrases	(S1/2), S25, S26, S36/37/39, S45
Flash point	50 °C (122 °F; 323 K)
Explosive limits	1.4–11.7%
Lethal dose or concentration (LD, LC):
LD50 (median dose)	1.113 g kg−1(dermal, rabbit) 1.3 g kg−1(oral, rat)
LC50 (median concentration)	924 ppm (rat, 4 hr) 1027 ppm (mouse)
US health exposure limits (NIOSH):
PEL (Permissible)	TWA 10 ppm (50 mg/m3) [skin]
REL (Recommended)	TWA 10 ppm (50 mg/m3) [skin]
IDLH (Immediate danger)	100 ppm
Related compounds
Related alkanols	N-Methylethanolamine Dimethylethanolamine Diethanolamine N,N-Diisopropylaminoethanol Methyl diethanolamine Triethanolamine Bis-tris methane Meglumine
Related compounds	Diethylhydroxylamine
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

Diethylethanolamine can be used as a precursor chemical to procaine. It can be reacted with 4-aminobenzoic acid to make procaine.

Diethylethanolamine is used as a corrosion inhibitor in steam and condensate lines by neutralizing carbonic acid and scavenging oxygen.

Diethylethanolamine is prepared commercially by the reaction of diethylamine and ethylene oxide.

It is also possible to prepare it by the reaction of diethylamine and ethylene chlorohydrin.

Diethylethanolamine is an irritant to the eyes, skin, and respiratory system. The Occupational Safety and Health Administration and the National Institute for Occupational Safety and Health have set occupational exposure limits for workers handling the chemical at 10 ppm (50 mg/m³) over an eight-hour workday.