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Cholecystokinin receptor

cholecystokinin A receptor
Identifiers
Symbol CCKAR
Entrez 886
HUGO 1570
OMIM 118444
RefSeq NM_000730
UniProt P32238
Other data
Locus Chr. 4 p15.2-p15.1
cholecystokinin B receptor
Identifiers
Symbol CCKBR
Entrez 887
HUGO 1571
OMIM 118445
RefSeq NM_176875
UniProt P32239
Other data
Locus Chr. 11 p15.4

Cholecystokinin receptors or CCK receptors are a group of G-protein coupled receptors which bind the peptide hormones cholecystokinin (CCK) and gastrin. There are two different subtypes CCKA and CCKB which are ~50% homologous: Various cholecystokinin antagonists have been developed and are used in research, although the only drug of this class that has been widely marketed to date is the anti-ulcer drug proglumide.



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