CYP2C8

Available structures

Ortholog search: PDBe RCSB

List of PDB id codes
2VN0, 1PQ2, 2NNH, 2NNI, 2NNJ

Identifiers

Aliases

CYP2C8, CPC8, CYPIIC8, MP-12/MP-20, cytochrome P450 family 2 subfamily C member 8

External IDs

OMIM: 601129 MGI: 1306819 HomoloGene: 117948 GeneCards: CYP2C8

Genetically Related Diseases

smallpox, osteonecrosis

Targeted by Drug

phenelzine

Gene ontology
Molecular function	• oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen • caffeine oxidase activity • aromatase activity • oxidoreductase activity • heme binding • metal ion binding • iron ion binding • arachidonic acid epoxygenase activity • oxygen binding • monooxygenase activity • estrogen 16-alpha-hydroxylase activity
Cellular component	• endoplasmic reticulum • organelle membrane • membrane • intracellular membrane-bounded organelle • endoplasmic reticulum membrane
Biological process	• omega-hydroxylase P450 pathway • organic acid metabolic process • epoxygenase P450 pathway • drug metabolic process • oxidative demethylation • xenobiotic metabolic process • exogenous drug catabolic process • oxidation-reduction process • lipid hydroxylation • steroid metabolic process
Sources:Amigo / QuickGO

RNA expression pattern

More reference expression data

Orthologs

Species

Human

Mouse

Entrez


1558


13097

Ensembl


ENSG00000138115


ENSMUSG00000032808

UniProt


P10632


P56655

RefSeq (mRNA)


NM_000770 NM_001198853 NM_001198854 NM_001198855 NM_030878


NM_010002

RefSeq (protein)


NP_000761 NP_001185782 NP_001185783 NP_001185784


NP_034132.2 NP_034132

Location (UCSC)

Chr 10: 95.04 – 95.07 Mb

Chr 19: 39.39 – 39.46 Mb

PubMed search

2VN0, 1PQ2, 2NNH, 2NNI, 2NNJ

NM_000770
NM_001198853
NM_001198854
NM_001198855
NM_030878

NM_010002

NP_000761
NP_001185782
NP_001185783
NP_001185784

NP_034132.2
NP_034132

...
Wikipedia