CXCR4

Available structures

Ortholog search: PDBe RCSB

List of PDB id codes
4RWS, 2K03, 2K04, 2K05, 3ODU, 3OE0, 3OE6, 3OE8, 3OE9, 2N55

Identifiers

CXCR4, CD184, D2S201E, FB22, HM89, HSY3RR, LAP-3, LAP3, LCR1, LESTR, NPY3R, NPYR, NPYRL, NPYY3R, WHIM, WHIMS, C-X-C motif chemokine receptor 4

External IDs

Targeted by Drug

Gene ontology
Molecular function	• cytokine binding • coreceptor activity • virus receptor activity • signal transducer activity • protein binding • chemokine receptor activity • myosin light chain binding • actin binding • ubiquitin protein ligase binding • G-protein coupled receptor activity • C-X-C chemokine receptor activity • ubiquitin binding
Cellular component	• cytoplasm • integral component of membrane • endosome • membrane • cell surface • cell junction • cell leading edge • extracellular exosome • cytoplasmic vesicle • early endosome • late endosome • lysosome • plasma membrane
Biological process	• myelin maintenance • positive regulation of oligodendrocyte differentiation • response to hypoxia • positive regulation of cytosolic calcium ion concentration • chemokine-mediated signaling pathway • response to virus • dendritic cell chemotaxis • cellular response to cytokine stimulus • chemotaxis • activation of MAPK activity • inflammatory response • calcium-mediated signaling • entry into host cell • signal transduction • apoptotic process • viral process • fusion of virus membrane with host plasma membrane • G-protein coupled receptor signaling pathway • regulation of chemotaxis
Sources:Amigo / QuickGO

Orthologs

Species

Human

Mouse

Entrez


7852


12767


ENSG00000121966


ENSMUSG00000045382


P61073


P70658

RefSeq (mRNA)


NM_003467 NM_001008540


NM_009911

RefSeq (protein)


NP_001008540 NP_003458 NP_001334985 NP_001334988 NP_001334989


NP_034041.2 NP_034041

Location (UCSC)

PubMed search